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Patients over 16 who have received an allogenic stem cell transplant to treat either AML or high risk MDS. This treatment now needs to be tested on more patients to see if the benefit is great enough for Azacitidine to be given to all MDS and AML patients post-transplant. There is now evidence to suggest that Azacitidine could also reduce the chance of the blood cancer returning after transplant. This is why clinicians are looking for ways to improve a type of treatment called maintenance therapy that prevents relapse after transplant.Īzacitidine is a chemotherapy drug that is already given as a treatment to patients with AML or MDS who cannot have a stem cell transplant.
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Unfortunately, sometimes the original leukaemia comes back, which is known as relapse.
Amadeus syndrome trial#
Why is the trial important?Ī stem cell transplant can result in long-term survival for many patients. To see if taking the chemotherapy drug Azacitidine reduces the chance of acute myeloid leukaemia (AML) or high-risk myelodysplastic syndromes (MDS) coming back after a stem cell transplant. Support for parents, family and friends.Charities that support you & your mental health.Taking control of your recovery & living well.Your mental health after a stem cell transplant.Late effects after a stem cell transplant.Looking after your mental health during your transplant.
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Medical appointments and planning ahead.Coronavirus (COVID-19) and your stem cell transplant.Finding a donor for your stem cell transplant.What is a matched unrelated donor transplant?.Different types of stem cell transplant.Medical options for blood cancers and disorders.Genetic blood disorders and other inherited conditions.